Medical symbolDirectory of Drugs: Prescription symbol Hydase - hyaluronidase injection


Patient Information Sheet
Hyaluronidase Injection (marketed as Hydase)

This is a summary of the most important information about Hydase.  For details, talk to your healthcare professional.

What is Hydase?

Hydase is an enzyme medicine that is injected under the skin:

  • with certain other injected medicines to help them pass into the body faster
  • with fluids in a process to replace lost fluids in the body when a person is unable to eat or drink
  • during an x-ray procedure called subcutaneous urography to help move contrast dye into the body

When should Hydase not be used?

Your healthcare professional should not give you Hydase if you are allergic to hyaluronidase or any of the inactive ingredients in Hydase.

What are the Risks?

The following are the major potential risks and side effects of Hydase therapy. However, this list is not complete.

Some common side effects with Hydase include:

  • injection site reactions, (such as pain at the injection site

  • swelling

  • itching

What should I tell my Healthcare Professional?

Tell your healthcare professional if you:

  • are pregnant, planning to become pregnant, or breast-feeding.
  • develop a rash, hives, itching, or swelling after being given Hydase or other hyaluronidase medicines. 

Can Other Medicines Or Food Affect Hydase?

Hydase and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.  Some medicines may affect how Hydase works or Hydase may affect how your other medicines work. 

 Know the medicines you take. Keep a list of them with you to show your healthcare professional.  

How will Hydase be given to me?

  • Your healthcare professional will inject Hydase under your skin.

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